Rosie Sixon was the first British woman to fight at UFC in 2013, and Macan appeared for the first time after five years.
Macan, a former fly champion in the promotion of the UK, Cage Woriors, won seven out of 14 paved in UFC, the most prominent of which is the exit of two yarn elbow in 2022.
She leaves sport after she won six of her tips with a knockout and demands three rewards at night, and it is more than others in the history of the UFC fly.
Maccane said she wanted to retire at home with her friends and family to attend.
“The camps are very difficult, and to keep everything together, it is difficult not to get win and damage,” she said.
Her retirement comes after four defeats in her past five battles.
Macan said: “UFC and Dana (UFC Dana White), this sport started in 24 years and I gave you all my heart and soul.”
“Tonight, with this performance within a week, it's not good enough. UFC deserves more.
“From a little girl from Norris Green Fighting in the squares – look at me, look at what I was able to do.”