The obesity conference hears how daily birth control pills have caused digestion of food to exceed a portion of the stomach until the lowest calories are absorbed
The inventors say that “infectious helicopter in birth control pills” can help diet specialists feel faster and climbing pounds.
The new daily tablet produces a paint in the upper part of the intestine, and digestion moves to the bottom where the full hormones are turned on.
The Syntis Bio manufacturer believes it may become “Go to Drug weight management” because it will have lower side effects than strong injection that supports appetite.
Infectious bypass operations are carried out by NHS on dangerous obesity for more than 20 years. It involves creating a small stomach bag and connecting it directly to the small intestine, transcending the rest of the stomach and the upper part of the small intestine. This reduces the body's ability to absorb calories and causes the release of the main hormones.
A new study, presented at the European Obesity Conference in Malaga, Spain, on a pill operating in the same way. An enzyme is active in the intestine to create a temporary coating in the top of the intestine. Food cannot be absorbed through the paint and directs it to low parts of the intestine. Participants feel full before they absorb a lot of food, so eat less.
“We make this to restrict absorption at the top of the intestine, while the bottom of the intestine is still fully working and without obstacles. The intestine is three meters long, and this covers approximately 15 cm in the top,” said researcher Rahul Danda, President of Syntis Bio.
Glucose carrying tests revealed the delay in the absorption of glucose and in 30 and 60 minutes, the absorption of glucose was much lower than the non -healet patients. This delay indicates that absorption occurs later in the intestine, as expected, and not in the coated area of the twelve.
The experimental study was not designed to measure weight loss, but participants who receive a full dose of birth control pills, currently called Synt-101, have received blood tests to look at hormones associated with the feelings of fullness. They showed high levels of leptin and lower levels of gillin, in line with low eating.
The early stage experience indicated that the drug is safe and manufacturers believe that it will come with lower side effects, if any, compared to weight loss injections. However, more experiments are needed to prove this, and if it has led to constant weight loss.
Mr. Danda said: “What this is doing is the integration with the mucous membrane that secretes the body naturally, and this is in line with it.
“I expect the side effects to be minimal, and we haven't seen any yet in human tests. This is because we do not enter the bloodstream like the injection. It is a mechanical molecule, so it seems that we enter the supports, rather than a drug that behaves with the target as well.”