Britons Joe Salisbury and Neil Skowski defeated Argentines Sebastian Baez and Francisco Comisana 7-6 (7-1) and 6-4 in the first round.
The 10th seed is playing his first Grand Slam together since Salisbury parted ways with his old partner Rajeev Ram after winning four Grand Slam titles, including the 2020 Australian Open, with the American.
Henry Patten and Finland's Hari Heilovaara, the Wimbledon champions, defeated Indian Rithvik Choudhary Bulipally and American Ryan Seagerman 7-6 (7-5) and 6-1.
Luke Johnson, along with Dutchman Sander Arends, defeated Spaniards Pablo Carreno Busta and Sergio Martos Jornes.
In the women's doubles, Britain's Harriet Dart and France's Diane Barry defeated Britain's Heather Watson and Czech Linda Noskova 6-3, 7-5.
Olivia Nichols and Slovakian Tereza Mihaljkova were eliminated from the tournament by Jelena Ostapenko from Latvia and Hsieh Su-wei from Taiwan, the third seeds, while Tara Moore and Austrian Julia Grabher lost to Americans Sabrina Santamaria and Bernarda Pera.
Lloyd Glasspool and Russian Alexandra Panova defeated Belgian Joran Vliegen and Spaniard Cristina Buxa 6-4, 1-6, 10-8 in the mixed doubles, but Jamie Murray and American Bethanie Mattek-Sands fell to them 6-3, 3-6, 11. -9 defeat to Australians Alex Bolt and Priscilla Hone.
